University of Tübingen

 

The group of Oliver Kohlbacher was founded in 2003 and concentrates on the design of drugs, immunoinformatics, structural bioinformatics and bioinformatics applications in proteomics, metabolomics and system biology. The group cooperates very closely with a wide variety of experimental groups in order to access current and relevant data sets.

In addition to classical methods of structural bioinformatics, methodological combinatorial optimization, graph theory, and machine learning are the focus. In order to make the methods available, we are developing large-scale open-source software packages in bioinformatics, e.g. BALL (structural bioinformatics), OpenMS (proteomics) and BiNA (network analysis).


References to specific research topics:

OpenMS – A platform for reproducible analysis of mass spectrometry data
Pfeuffer, JU, Sachsenberg, T, Alka, O, Walzer, M, Fillbrunn, A, Nilse, L, Schilling, O, Reinert, K, and Kohlbacher, O.
J. Biotechnol.:S0168-1656(17)30251-1 (2017).

ImmunoNodes – Graphical Development of Complex Immunoinformatics Workflows
Schubert, B, de la Garza, L, Mohr, C, Walzer, M, and Kohlbacher, O.
BMC Bioinformatics (2017)

Learning from Heterogeneous Data Sources: An Application in Spatial Proteomics
Breckels, LM, Holden, S, Wojnar, D, Mulvey, CM, Christoforou, A, Groen, A, Kohlbacher, O, Lilley, KS, and Gatto, L.
PLoS Comput. Biol., 12(5):e1004920 (2016).

Mass Spectrometry-based Proteomics Reveals Organspecific Expression Patterns To Be Used as Forensic Evidence
Dammeier, S, Nahnsen, S, Veit, J, Wehner, F, Ueffing, M, and Kohlbacher, O.
J. Proteome Res., 15(1):182-92 (2016).

From the Desktop to the Grid and Cloud: Conversion of KNIME Workflows to gUSE
de la Garza, L, Aicheler, F, and Kohlbacher, O.
Proc. Int. Workshop Science Gateways (IWSG 2016).

From the Desktop to the Grid: scalable Bioinformatics via Workflow Conversion
de la Garza, L, Veit, J, Szolek, A, Röttig, M, Aiche, S, Gesing, S, Reinert, K, and Kohlbacher, O.
BMC Bioinformatics, 17(1):127 (2016).

Contact

 

Prof. Dr.-Ing. Oliver Kohlbacher
University of Hamburg
Department of Informatics
Sand 14
72076 Tübingen

Fon: +49-7071-29-70458
oliver.kohlbacher@uni-tuebingen.de
http://kohlbacherlab.org/